Is the new line item in a PO synced to Xero if the initial PO has already been synced? Yes, it will be synced in the same PO when synced to Xero. The bill will be updated in Xero. Related articles Can I map multiple SKUs for eBay or Amazon? If I change the Ship From Location in ShipStation, will it sync back to QuickBooks Commerce? What is the Unit Cost on my Stock Transfer? Accounting for Manufacturing Purchase Orders Overview