Is the new line item in a PO synced to Xero if the initial PO has already been synced? Yes, it will be synced in the same PO when synced to Xero. The bill will be updated in Xero. Related articles Can I map multiple SKUs for eBay or Amazon? Does QuickBooks Commerce automatically sync variant description to QBO once added? How do I fix this error: 'Your Payments ledger account on Xero is not enabled for payments'? What is the difference between Stock Purchases and Purchases ledger account? How do I export Sales Orders from QuickBooks Commerce?